Large language models (LLMs) have gained significant traction in medical decision support systems, particularly in the context of medical question answering and role-playing simulations. A common practice, Prompt-Based Role Playing (PBRP), instructs models to adopt different clinical roles (e.g., medical students, residents, attending physicians) to simulate varied professional behaviors. However, the impact of such role prompts on model reasoning capabilities remains unclear. This study introduces the RP-Neuron-Activated Evaluation Framework(RPNA) to evaluate whether role prompts induce distinct, role-specific cognitive processes in LLMs or merely modify linguistic style. We test this framework on three medical QA datasets, employing neuron ablation and representation analysis techniques to assess changes in reasoning pathways. Our results demonstrate that role prompts do not significantly enhance the medical reasoning abilities of LLMs. Instead, they primarily affect surface-level linguistic features, with no evidence of distinct reasoning pathways or cognitive differentiation across clinical roles. Despite superficial stylistic changes, the core decision-making mechanisms of LLMs remain uniform across roles, indicating that current PBRP methods fail to replicate the cognitive complexity found in real-world medical practice. This highlights the limitations of role-playing in medical AI and emphasizes the need for models that simulate genuine cognitive processes rather than linguistic imitation.We have released the related code in the following repository:https: //github.com/IAAR-Shanghai/RolePlay_LLMDoctor

Question answering (QA) plays a central role in financial education, yet existing large language model (LLM) approaches often fail to capture the nuanced and specialized reasoning required for financial problem-solving. The financial domain demands multistep quantitative reasoning, familiarity with domain-specific terminology, and comprehension of real-world scenarios. We present a multi-agent framework that leverages role-based prompting to enhance performance on domain-specific QA. Our framework comprises a Base Generator, an Evidence Retriever, and an Expert Reviewer agent that work in a single-pass iteration to produce a refined answer. We evaluated our framework on a set of 3,532 expert-designed finance education questions from Study.com, an online learning platform. We leverage retrieval-augmented generation (RAG) for contextual evidence from 6 finance textbooks and prompting strategies for a domain-expert reviewer. Our experiments indicate that critique-based refinement improves answer accuracy by 6.6-8.3% over zero-shot Chain-of-Thought baselines, with the highest performance from Gemini-2.0-Flash. Furthermore, our method enables GPT-4o-mini to achieve performance comparable to the finance-tuned FinGPT-mt_Llama3-8B_LoRA. Our results show a cost-effective approach to enhancing financial QA and offer insights for further research in multi-agent financial LLM systems.

High-quality prompts are crucial for eliciting outstanding performance from large language models (LLMs) on complex tasks. Existing research has explored model-driven strategies for prompt optimization. However, these methods often suffer from high computational overhead or require strong optimization capabilities from the model itself, which limits their broad applicability.To address these challenges, we propose ORPP (Optimized Role-Playing Prompt),a framework that enhances model performance by optimizing and generating role-playing prompts. The core idea of ORPP is to confine the prompt search space to role-playing scenarios, thereby fully activating the model's intrinsic capabilities through carefully crafted, high-quality role-playing prompts. Specifically, ORPP first performs iterative optimization on a small subset of training samples to generate high-quality role-playing prompts. Then, leveraging the model's few-shot learning capability, it transfers the optimization experience to efficiently generate suitable prompts for the remaining samples.Our experimental results show that ORPP not only matches but in most cases surpasses existing mainstream prompt optimization methods in terms of performance. Notably, ORPP demonstrates superior "plug-and-play" capability. In most cases, it can be integrated with various other prompt methods and further enhance their effectiveness.

The Gartner 2022 report predicts that 45% of organizations worldwide will encounter software supply chain attacks by 2025, highlighting the urgency to improve software supply chain security for community and national interests. Current malware detection techniques aid in the manual review process by filtering benign and malware packages, yet such techniques have high false-positive rates and limited automation support. Therefore, malware detection techniques could benefit from advanced, more automated approaches for accurate and minimally false-positive results. The goal of this study is to assist security analysts in identifying malicious packages through the empirical study of large language models (LLMs) to detect potential malware in the npm ecosystem. We present SocketAI Scanner, a multi-stage decision-maker malware detection workflow using iterative self-refinement and zero-shot-role-play-Chain of Thought (CoT) prompting techniques for ChatGPT. We studied 5,115 npm packages (of which 2,180 are malicious) and performed a baseline comparison of the GPT-3 and GPT-4 models with a static analysis tool. Our findings showed promising results for GPT models with low misclassification alert rates. Our baseline comparison demonstrates a notable improvement over static analysis in precision scores above 25% and F1 scores above 15%. We attained precision and F1 scores of 91% and 94%, respectively, for the GPT-3 model. Overall, GPT-4 demonstrates superior performance in precision (99%) and F1 (97%) scores, while GPT-3 presents a cost-effective balance between performance and expenditure.

The growing interest in Large Language Models (LLMs) for specialized applications has revealed a significant challenge: when tailored to specific domains, LLMs tend to experience catastrophic forgetting, compromising their general capabilities and leading to a suboptimal user experience. Additionally, crafting a versatile model for multiple domains simultaneously often results in a decline in overall performance due to confusion between domains. In response to these issues, we present the RolE Prompting Guided Multi-Domain Adaptation (REGA) strategy. This novel approach effectively manages multi-domain LLM adaptation through three key components: 1) Self-Distillation constructs and replays general-domain exemplars to alleviate catastrophic forgetting. 2) Role Prompting assigns a central prompt to the general domain and a unique role prompt to each specific domain to minimize inter-domain confusion during training. 3) Role Integration reuses and integrates a small portion of domain-specific data to the general-domain data, which are trained under the guidance of the central prompt. The central prompt is used for a streamlined inference process, removing the necessity to switch prompts for different domains. Empirical results demonstrate that REGA effectively alleviates catastrophic forgetting and inter-domain confusion. This leads to improved domain-specific performance compared to standard fine-tuned models, while still preserving robust general capabilities.